Younger group (n = 42) | Elderly group (n = 32) | G1/2 | |||||
n (% of patients) | n (% of patients) | ||||||
Toxicity | G 1/2 | G 3/4 | G 1/2 (%) | G 1/2 | G 3/4 | G 1/2 (%) | p value |
Nausea | 24 | 0 | 57.1 | 18 | 0 | 56.3 | 0.9388 |
Vomiting | 5 | 0 | 11.9 | 3 | 0 | 9.4 | 0.7284 |
Anorexia | 33 | 0 | 78.6 | 25 | 0 | 78.1 | 0.9631 |
Fatigue | 32 | 0 | 76.2 | 26 | 0 | 81.3 | 0.6004 |
Diarrhea | 4 | 0 | 9.5 | 0 | 0 | 0 | 0.0727 |
Constipation | 14 | 0 | 33.3 | 13 | 0 | 40.6 | 0.5186 |
AST/ALT | 20 | 0 | 47.6 | 13 | 0 | 40.6 | 0.5487 |
Creatinine | 1 | 0 | 2.4 | 3 | 0 | 9.4 | 0.1875 |
Neuropathy | 0 | 0 | 0 | 0 | 0 | 0 | - |
Pain, joint | 3 | 0 | 7.1 | 1 | 0 | 3.1 | 0.4489 |
Pain, muscle | 1 | 0 | 2.4 | 3 | 0 | 9.4 | 0.1875 |
Skin rash | 5 | 0 | 11.9 | 2 | 0 | 6.3 | 0.4102 |
Alopecia | 12 | 0 | 28.6 | 14 | 0 | 43.8 | 0.1754 |
Infection | 1 | 0 | 2.4 | 0 | 1* | 0 | 0.3795 |
Fever | 6 | 0 | 14.3 | 3 | 0 | 9.4 | 0.522 |
Others | 3 | 0 | 7.1 | 1 | 0 | 3.1 | 0.4489 |